KORPM

Predicting the effect of mutations on protein stability based on our Knowledge-base ORientational Potential  (KORP).  KORPM offers the most efficient alternative to estimate protein stability from a 3D structure with an accuracy comparable, if not better than currently available methods. The method including code, documentation, test and training dataset is fully available on github/chaconlab/korpm

References


Chacón P. et al.  (2022) Predicting protein stability changes upon mutation using a simple orientational potential.  (to be published)

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