• Home
  • Hybrid methods for EM

Hybrid methods for EM

Computational hybrid methods bridge the gap between different experimental techniques such as cryo-electron microscopy and X-ray crystallography by combining their multiresolution structural information. Firstly, we helped to develop the pioneering EM modeling package Situs. Complementary rigid-body fitting ADP_EM and flexible fitting iMODfit have been successfully applied in a variety of fitting real scenarios.