iMORPH intro

IMORPH calculates feasible transition pathways between two different conformations of proteins or nucleic acids. This is a very versatile tool to explore potential pathways even between two relatively distant homolog structures (e.g. sequence number mismatch are allowed). We are currently improving this tool but meanwhile you can have access to the latest version either from iMODS online server or from the command line executable included in iMOD toolkit.

References


José Ramón Lopéz-Blanco, José Ignacio Garzón and Pablo Chacón. iMod: multipurpose normal mode analysis in internal coordinates. Bioinformatics (2011) 27 (20): 2843-2850.